Purpose of the Study

The purpose of the study is to learn how a combination of Jardiance and the investigational study drug may work in people with heart failure and low heart pumping strength (LVEF less than 40%). The study will compare this combination to Jardiance and placebo, both given in alignment with standard heart failure care.

Study Requirements

You may qualify if you:

o Are 18 years of age or older
o Have been diagnosed with chronic heart failure (NYHA Class II–IV)
o Have reduced heart function (LVEF less than 40%)
o Are taking standard heart failure medications like an ACE inhibitor, ARB, ARNI, beta-blocker, or SGLT2 inhibitor
o Are not currently taking MRA medications (like spironolactone or eplerenone)

Potential Benefits of Participation

Maginfying

Access to new treatments that are not yet available to the general public.

Hand Heart

Personalized medical attention from leading healthcare professionals.

Helios

Compensation up to $2485.00 may be provided for study-related time and travel.

Study Locations

This study is currently enrolling at the following sites:

Helios Clinical Research - Fort Worth – 1307 8th Avenue, 76104

About Helios Clinical

Helios Clinical is dedicated to advancing medical research through innovative clinical trials.
Our mission is to discover new ways to improve patient health and outcomes.
We collaborate with leading healthcare professionals and scientists
to ensure the highest standards of research and care for our participants.